Posts Tagged ‘IVF’

80% Pregnant Women Low in Vitamin D

Friday, July 23rd, 2010

pregnancytestWidespread vitamin D deficiency among pregnant women suggests that antenatal screening for deficiency should be extended to all women, not just those traditionally considered to be at high risk, Australian researchers say.

A study in a region of northern Victoria found that around 80% of low-risk pregnant women have insufficient vitamin D levels, 28% have mild deficiency during the winter months and 7% have moderate to severe deficiency.

The study of more than 330 women attending routine antenatal clinics in Shepparton also found that deficiency was also present in the summer months, with 50% of pregnant women having insufficient vitamin D levels (between 50 and 75mmol/L), 12% having mild vitamin D deficiency (25-50mmol/L) and 3% having moderate to severe deficiency.

The findings, published in the Australia and NZ Journal of Obstetrics and Gynaecology may explain why some children in the region still develop rickets even though there is abundant sunshine, say the study authors from the Rural Clinical School of the University of Melbourne. They note that vitamin D deficiency was almost universal in women in their study who were from high risk groups such as those from Arabic backgrounds.

“However, our study would support routine testing for all antenatal women, as even apparently low risk women are commonly vitamin D deficient,” they write. The only question remaining is over the optimum level of supplementation, they say, with some doubt about whether the daily supplements of 800IU of vitamin D a day may be insufficient to raise vitamin D levels.

Acupuncture - Why You Should Do It

Tuesday, July 20th, 2010

fit-woman1Acupuncture treatments appear to help to reduce insulin resistance, according to a report just released from the Kanazawa Medical University in Japan. Acupuncture has been practiced for thousands of years in China and has been increasingly used worldwide for insulin resistance-related diseases.

The report was based on the analysis of 234 publications on the effectiveness of acupuncture as a treatment for problems related to insulin resistance. All together, these publications provide clinical evidence indicating that acupuncture is effective for reducing insulin resistance.

Researchers at Goteborg University in Sweden published a review article on acupuncture for PCOS. They concluded: “Clearly, acupuncture can affect PCOS via modulation of…the sympathetic nervous system, the endocrine and the neuroendocrine system.”

Have you overlooked acupuncture as a wholistic way to help you deal with polycystic ovary syndrome and insulin resistance? I love acupuncture and always tell women going through IVF to have sessions before and after their embryo transfer. Acupuncture is also fantastic when women are overdue with their pregnancy and a very easy, non invasive way to get labour started. Maybe you should give it a try.

Consider adding an experienced acupuncturist to your personal healthcare team. At Darling Street Health Centre we have a very experienced clinician, Lina Thornton who I can’t say enough great things about!

Sources: Liang F et al, Acupuncture: is it effective for treatment of insulin resistance?, Diabetes Obes Metab. 2010 Jul;12(7):555-69

Stener-Vuictorin E et al, Acupuncture in Polycystic Ovary Syndrome: Current Experimental and Clinical Evidence, J Neuroendocrinol. 2008 Mar;20(3):290-8

Mediterranean diet increases chances of pregnancy after infertility treatment

Sunday, July 18th, 2010

three-pregnant-womenThe diets of 161 women undergoing IVF treatment were evaluated to see if their dietary habits affected their chances of becoming pregnant.

Two main dietary patterns were observed: a healthy diet characterised by high intakes of fruit, vegetables, fish, and wholegrains, and a Mediterranean diet characterised by high intake of vegetable oils, vegetables, fish and beans.

Women who most closely adhered to a Mediterranean diet had a 40% greater chance of pregnancy after infertility treatment than those who ate the least Mediterranean-like diet.

In vitro fertilisation is a costly and emotionally stressful experience – anything that increases the chances of a successful pregnancy would be of huge benefit for thousands of women and couples. This study from the Netherlands found that adhering to a Mediterranean diet could increase the chances of success by 40%. The authors stress that this was an observational study and cause-and-effect have not been proved. But given that it is a very healthy diet anyway, it is strongly recommended for women undergoing IVF and the studies that prove that it works are eagerly awaited.

http://www.fertstert.org/article/S0015-0282(09)04338-6/abstract

Low iodine puts baby brains at risk

Thursday, June 17th, 2010

PregnancyHealth experts are urging pregnant women in Tasmania to take iodine supplements to lessen the chances of their children developing low IQ’s. The Director of Public Health, Dr Roscoe Taylor, says most Tasmanians are iodine deficient because of low levels in soil and water. He says the health consequences of iodine deficiency in pregnant and breastfeeding women is greater because of the risk to babies.

Dr Taylor says Iodine is essential to ensure normal development of the brain and nervous system. Low levels in pregnant mothers could result in their babies having lower IQ’s. He has written to all health practitioners around the state asking them to encourage expectant mothers to take an iodine supplement of 150 micrograms every day, equivalent to eating nine cans of tuna.

Iodine is a trace mineral. Iodine is vital for the thyroid hormones that regulate our metabolism, body temperature, reproduction, growth, blood cell production as well as nerve and muscle function. Low thyroid hormones can cause a person to become sluggish and gain weight, affecting their general health, their fertility and ability to carry a pregnancy.

It is important to ensure adequate iodine intake during preconception, pregnancy and breast feeding. During pregnancy, the foetus is entirely dependent upon maternal iodine, which plays a significant role in normal central nervous system formation and maturation. Iodine deficiency during pregnancy is the commonest worldwide cause of preventable intellectual impairment and can be associated with losses of up to 10 -15 IQ points.

Around 60% of pregnant Australian women in a recent survey had low iodine levels -mainly due to decreased consumption of iodised salt and changes within the dairy industry. The recently published Australian National Iodine Nutrition Study in the Medical Journal of Australia has called for “the urgent implementation of mandatory iodisation of all edible salt in Australia”. The study coordinator, Professor Creswell Eastman, said urgent action is required now as it will be years before the relevant laws are implemented. He recommends 250mcg of iodine daily for those planning conception, during pregnancy and when breast feeding.

A 2006 study involving 1,709 schoolchildren across the eastern seaboard of Australia demonstrated that 40% of children were iodine deficient. The researchers called for urgent implementation of mandatory iodisation of all edible salt in Australia. This shows that iodine deficiency is extremely common and can easily be addressed.

Many occupations are at a higher risk of iodine deficiency than others. This results as chemicals of a very similar structure called halogens successfully compete with iodine for absorption and disrupt iodine metabolism. These halogens include chlorine (swimming teachers), fluorine (dentists) and bromine (found in some medications).

Natural Sources of Iodine

Vegetables grown in iodine rich soils (mainly in coastal regions) and products from animals that eat these plants contain iodine. Iodine must be obtained regularly from the diet as it is not conserved for long term use. Supplementation should be supervised by a qualified naturopath.

Seafood – fish especially whiting, mackerel and cod, mussels

Vegetables – all but particularly beetroot, celery, fennel, spinach, lettuce, artichoke and mushrooms

Fruits – all but particularly grapes, pineapple and oranges

Seaweed

Celtic sea salt has the highest levels of iodine out of all salts

Measuring Iodine Levels

Iodine levels are measured in the urine – either via a single sample or a 24 hour collection. Ask Emma for further information about these tests.

Fertility Drugs May Increase Your Chance of Cancer

Tuesday, February 9th, 2010

A very interesting video on the effect of fertility drugs on cancer risk - mentioned is the number 1 fertility drug Clomid. I think the main thing to remember is that you need to ensure that you lower all your other risk factors for cancer in order to balance this out - improve your diet, eat organic, exercise, breathe deeply and see a naturopath to treat any existing problems. Click the link below:

Fertility Drugs may increase your chance of Cancer

Birth Choices Expo - Leichhardt March 5th

Sunday, January 24th, 2010

HypnoBirthing babyI am a proud sponsor of Birth Choices Expo. I believe everyone should have access to the information they need in order to make informed decisions about parenting. Parenting is one of the most rewarding, challenging and empowering things you can ever do. As I specialise in women’s health this means that I spend a lot of time with families, pregnant women and their babies.

The journey of preconception, pregnancy and birth can be greatly facilitated with naturopathic care and that is what I will be focusing on at the expo. I present regularly to doulas and midwives and share with them how natural medicine benefits their women.

Birth Choices Expo’s aim is to make information about pregnancy, birth & parenting more accessible so that you can make the right choices for you & your baby and experience the joy of parenting.

You will have the opportunity, in a relaxed atmosphere, to meet with:
•    Independent Midwives
•    Birth Centre Midwives
•    Doulas
•    Natural Health Practitioners
•    Parenting Experts
•    Other parents, including dads at the Men at Birth table
•    Plus enjoy speakers, food, free show bags & more…

So, put the date aside in your diary, grab your friends and come to see me at the Expo. I will have a few surprise give aways on the night but you will have to be there!

Vitamin D Linked to C-Section Births

Saturday, November 21st, 2009

pregnant-woman-doing-yogaCaesarean section rates are at an all time high in Australia (28.8%) and the United States (30.2%). As vitamin D is crucial for proper muscle function, the researchers examined the relationship between vitamin D deficiency and caesarean section rates. Between 2005 and 2007, 253 women who gave birth in a Massachusetts hospital were found to be nearly four times more likely to have a caesarean section if their serum vitamin D levels were below 37.5nmol/L than those levels at 37.5nmol/L or greater. The authors concluded that vitamin D deficiency is associated with an increased risk of caesarean section.
Vitamin D has been receiving so much research over the last few years and this study demonstrates the broader functions of vitamin D. Absolutely insist that your vitamin D levels are monitored throughout pregnancy and supplement if necessary – remember that you need to use the D3 form!

Association between vitamin D deficiency and primary caesarean section.

BACKGROUND: At the turn of the 20th century, women commonly died in childbirth due to rachitic pelvis. Although rickets virtually disappeared with the discovery of the hormone vitamin D, recent reports suggest vitamin D deficiency is widespread in industrialized nations. Poor muscular performance is an established symptom of vitamin D deficiency. The current U.S. caesarean birth rate is at an all-time high of 30.2%. We analysed the relationship between maternal serum 25-hydroxyvitamin D [25(OH) D] status, and prevalence of primary caesarean section. METHODS: Between 2005 and 2007, we measured maternal and infant serum 25(OH) D at birth and abstracted demographic and medical data from the maternal medical record at an urban teaching hospital (Boston, MA) with 2500 births per year. We enrolled 253 women, of whom 43 (17%) had a primary caesarean. RESULTS: There was an inverse association with having a caesarean section and serum 25(OH) D levels. We found that 28% of women with serum 25(OH)D less than 37.5 nmol/litre had a caesarean section, compared with only 14% of women with 25(OH)D 37.5nmol/litre or greater (P = 0.012). In multivariable logistic regression analysis controlling for race, age, education level, insurance status, and alcohol use, women with 25(OH)D less than 37.5 nmol/litre were almost 4 times as likely to have a caesarean than women with 25(OH)D 37.5 nmol/litre or greater (adjusted odds ratio 3.84; 95% confidence interval 1.71 to 8.62). CONCLUSION: Vitamin D deficiency was associated with increased odds of primary caesarean section.

J Clin Endocrinol Metab. 2009 Mar; 94(3):940-5.
PMID: 19106272

The Concept of IntraUterine Pollution

Saturday, November 21st, 2009

three-pregnant-womenThree years ago Dr. Michael Odent, a world renowned leader in the field of obstetrics, stated that “human health is shaped to a great extent during intrauterine life and prenatal pollution is a threat for the health of future generations”.  Such an accumulation of research demonstrates that there are enormous implications in terms of public health – nothing is more important today than the health and wellbeing of pregnant women. We need to address the importance of nutrition before the conception of the baby, as a way to prepare the intrauterine environment.

One important factor that Dr. Odent considers is the effect of fat soluble synthetic chemicals on health. Over the years we have accumulated hundreds of chemicals in our adipose tissue that would not have been there 60 years ago as such chemicals didn’t exist. Many of these chemicals have a long half life and we do not have the enzymes required to break them down for excretion. During the time an embryo is nourished in the uterus, molecules used by cells to “talk” to each other affect the way that genes are expressed. This ability of the environment to “turn on” or “turn off” a gene is studied in the fascinating science called Epigenetics. This is a field that I am particularly interested in and there are many emerging studies that are shedding light on this.

Going back to fat soluble chemicals, many of them are biologically active at very small amounts, usually too small to be detected in standard testing procedures. Just because a substance is not detected on a test does not mean that it is harmless! We now have strong conclusive evidence that the increasing rates of male genital tract disorders such as cancer of the testicles and reduced average sperm counts is due to the effect of these accumulated chemicals in adipose tissue acting as endocrine disruptors.

So, one of the protocols in my preconception program is a thorough detox that aides the safe elimination of many fat soluble synthetic chemicals. I have been working with detoxification for many years and through my time at the Golden Door Health Retreat I was able to fine tune a program that supports wholistic health.

New Infertility Treatments In the Near Future?

Saturday, November 21st, 2009

spermSo, what do you think about the latest development in fertility research? Feel free to share with me your opinions – is this a positive breakthrough or is this going too far?

Infertility treatments based on artificial sperm and eggs could be available within a decade as British research indicates it is possible to grow them from human embryonic stem (ES) cells. British scientists claimed to have created human sperm from embryonic stem cells for the first time, an accomplishment they say may someday help infertile men father children.

The technique could in 10 years allow researchers to use the basic knowledge of how sperm develop to design treatments to enable infertile men the chance to have biological children, said lead researcher Karim Nayernia, of Newcastle University, whose team earlier produced baby mice from sperm derived in a similar way. The research, published in the journal Stem Cells and Development, was conducted by scientists at Newcastle and the NorthEast England Stem Cell Institute.

Stem cells can become any cell in the body, and scientists have previously turned them into a variety of new entities, including cells from the brain, pancreas, heart and blood vessels. Some experts challenged the research, saying they weren’t convinced Nayernia and his colleagues had actually produced sperm cells. Several critics also said the sperm cells they created were clearly abnormal. “I am unconvinced from the data presented in this paper that the cells produced by Professor Nayernia’s group from embryonic stem cells can be accurately called ’spermatazoa,” said Allan Pacey, a senior lecturer in andrology at the University of Sheffield.

Pacey said in a statement that the sperm created by Nayernia did not have the specific shape, movement and function of real sperm. Azim Surani, a professor of physiology and reproduction at the University of Cambridge said the sperm produced by the Newcastle team were “a long way from being authentic sperm cells.”

Nayernia said the cells “showed all the characteristics of sperm,” but his group’s intention was simply to “open up new avenues of research” with their early findings, rather than using the sperm to fertilize eggs.  Robin Lovell-Badge, a stem cell expert at the National Institute of Medical Research said that despite the questions raised, Nayernia and colleagues may have made some progress in obtaining human sperm from embryonic cells.

DHEA May Optimise Fertility in Combination with IVF

Saturday, November 21st, 2009

pregnancytestDHEA is a natural steroid hormone produced from cholesterol by the adrenal glands, and in the body it is converted into testosterone and estrogen. The most abundant of all steroid hormones in humans, DHEA declines as we age. The concept in regards to fertility is that androgens may augment FSH-receptor expression and stimulate granulosa cell proliferation. This could potentially increase oocyte yield, by increasing the number of follicles responding to exogenous FSH administration and by improving the quality and pregnancy potential of the retrieved oocytes.

“Apparently the maximum effect of DHEA kicks in only after about four months,” says leading fertility researcher Dr Norman Gleicher. It’s also important to note that Gleicher thinks that DHEA can only boost egg production when used in combination with prescribed fertility drugs. “In a natural cycle, it doesn’t matter how many eggs a woman produces. In the end her body will release usually only one,” he explains. “When you are on fertility drugs we make the body release more eggs. And so in order to get the full benefit of DHEA, it is very likely that it will have to be taken in combination with fertility drugs so that the woman does release more than just one egg.”

Dr Gleicher has begun to conduct a larger controlled, double-blind study that might offer more concrete proof that DHEA can increase egg yield in older women. The results are due out in March 2010 but in the meantime, read below for his initial research literature results.

For optimal fertility health, it is vital to look at the health of your adrenal glands and support them using natural therapies. Stress has a huge impact on our adrenal glands, as they are activated when we feel tense or anxious. Adrenaline is secreted by the adrenals and it is very common for patients to present with the symptoms of adrenal fatigue. These include:

• Cravings for sugar
• Cravings for salt on food when you eat
• Feel dehydrated and thirsty and require plenty of water
• Difficulty falling asleep at night, sleep lightly or wake early or often
• Difficulty relaxing, nervous, anxious or hyperactive
• Often spacey, or foggy thinking, even memory loss
• Lack willpower to accomplish
• General exhaustion
• Hormone imbalances
• Low libido
• Weight gain, especially in abdomen and waist area
• Losing muscle tone

So, if you are suffering from more than three of the above symptoms then it is time that you started to support your adrenal glands. There are many herbal medicines and therapeutic nutrients that will help you to address adrenal fatigue. Ask me at your next appointment to begin addressing your adrenal gland health.


Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo grade and cell number in IVF

BACKGROUND: The aim of this study was to investigate the effect of treatment with dehydroepiandrosterone (DHEA) on fertility outcomes among women with diminished ovarian reserve. MATERIALS AND METHODS: This is a case–control study in an academically affiliated private infertility centre. Twenty-five women with significantly diminished ovarian reserve had one IVF cycle before and after DHEA treatment, with otherwise identical hormonal stimulation. Women received 75 mg of DHEA daily (25 mg three times daily) for an average of 17.6 ± 2.13 weeks. We performed a comparison of IVF outcome parameters, before and after DHEA treatment, including peak estrodiol (E2) levels, oocyte and embryo numbers, oocyte and embryo quality and embryo transfer statistics. RESULTS: Paired analysis of IVF cycle outcomes in 25 patients, who underwent cycles both before and after DHEA supplementation, demonstrated significant increases in fertilized oocytes (P < 0.001), normal day 3 embryos (P = 0.001), embryos transferred (P = 0.005) and average embryo scores per oocyte (P < 0.001) after DHEA treatment. CONCLUSION: This study confirms the previously reported beneficial effects of DHEA supplementation on ovarian function in women with diminished ovarian reserve.

Human Reproduction 2006 21(11):2845-2849; doi:10.1093/humrep/del254